Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment

Model NO.: 2627-69-2
Quality Standard: Bp, USP, Ep, Cp
Usage: Body Building
Appearence: White Powder
Payment Method: T/T, Western Union, Money Gram, Paypal
Delivery Time: Shipped in 3 Days After Payment
Shipping Method: EMS, DHL, FedEx, etc(Door-to-Door)
Trademark: Shinrezing
Transport Package: Foil Bag, Drum or Carton (Discreet Package)
Origin: Hubei
HS Code: 3001200010
Model NO.: 2627-69-2
Quality Standard: Bp, USP, Ep, Cp
Usage: Body Building
Appearence: White Powder
Payment Method: T/T, Western Union, Money Gram, Paypal
Delivery Time: Shipped in 3 Days After Payment
Shipping Method: EMS, DHL, FedEx, etc(Door-to-Door)
Trademark: Shinrezing
Transport Package: Foil Bag, Drum or Carton (Discreet Package)
Origin: Hubei
HS Code: 3001200010

Product Description
Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment

Acadesine/AICAR Powder CAS:2627-69-2

Alias:AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE
CAS:2627-69-2
EINECS:220-097-5
Molecular Formula:C9H14N4O5
Molecular Weight:258.23
Apperance: White or off-white powder.

Acadesine/AICAR Powder Description:

1. AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide.It can also be known as AICA ribonucleotide, ZMP, or Acadesine.It is an intermediate contained in the generation of inosine monophosphate.It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production.

2. AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).

3. AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion.

4. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion.Additionally, the peptide's presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.

Acadesine/AICAR Powder Biological Activity:

1. AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

2. Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCsin vitro.

Acadesine/AICAR Powder Functions:

1. AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.

2. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).

3. The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.

Analysis Report:
 

Item Specification Result
Appearance White powder Complies
Related substance (HPLC) Total impurity ≤0.5%
Max single impurity ≤0.1%		 0.2%
0.06%
Odor Characteristic Complies
Assay 99% 99.8%
Sieve analysis 100% pass 80 mesh Complies
Loss on Drying
Residue on Ignition		 ≤1.0%
≤1.0%		 0.12%
0.09%
Heavy Metal <10ppm Complies
As <0.1ppm 0.05ppm
Pb <0.1ppm 0.05ppm
Cd <0.1ppm 0.05ppm
Residual Solvents <100ppm Complies
Residual Pesticide Negative Complies
Microbiology    
Total Plate Count <1000cfu/g Complies
Yeast & Mold <100cfu/g Complies
E.Coli Negative Complies
Salmonella Negative Complies

 


Related Products 
Name CAS No. 
SR-9009 1165910-22-4
Rad-140 1182367-47-0
MK-677 159752-10-0
YK-11 431579-34-9
LGD-4033 1165910-22-4
GW-501516 317318-70-0
Andarine S4 401900-40-1
MK-2866 841205-47-8
Sunifiram 314728-85-3  
 

How to order quickly and safely? 

Step 1 (Inquiry) Please let me know the items you are favorable, quantities, and the destination country. 
Step 2 (Offer) We offer you price and the suitable shipping method for your reference. 
Step 3 (Negotiation) We will negotiate price, terms of payment, transport, delivery time, arrival time, destination of the goods and after-sales service. 
Step 4 (Order) After receiving your order, we will check it and get prepared for it. 
Step 5 (Payment) Please confirm the order and pay money 100% in advance, then send us the detailed contacting information, including contacting person/company, address, mobile number, ZIP code and your special requirements. 
Step 6 (Package & Delivery) Parcel will be arranged within 24 hours upon receipt of your payment. And photos will be offered to tell apart the products. 
Step 7 (Tracking number) If sent by EMS, the tracking number is availabe within 12 hours. The info will be trackable that day or next day. 
If sent by HKEMS or other express, the tracking number will be provided next day. And this does not mean the info is trackable that day. It will be released on internet 2 or 3 days later, because the parcel has to be shipped to Hongkong fist, and then wait for the flight. 
Step 8 (After-Sales Service) Within the terms of the contract, If there is any problem about the goods quality, quantity and other problems, we will assure you to make you satisfied with the results.  

Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment


  

Peptide List
 
Product Name Specification
ACE 031 1 mg/vial, 10 vials/kit
Follistatin 315 1 mg/vial, 10 vials/kit
Follistatin 344 1 mg/vial, 10 vials/kit
***************************** *****************************
Melanotan I 10 mg/vial, 10 vials/kit
Melanotan II 10 mg/vial, 10 vials/kit
MGF 2 mg/vial, 10 vials/kit
PEG - MGF 2 mg/vial, 10 vials/kit
DSIP 2 mg/vial, 10 vials/kit
TB500 2 mg/vial, 10 vials/kit
Oxytocin 2 mg/vial, 10 vials/kit
Hexarelin 2 mg/vial, 10 vials/kit
Triptorelin 2 mg/vial, 10 vials/kit
Ipamorelin 2 mg/vial, 10 vials/kit
Sermorelin 2 mg/vial, 10 vials/kit
Gonadorelin 2 mg/vial, 10 vials/kit
Tesamorelin 2 mg/vial, 10 vials/kit
BPC 157 2 mg/vial, 10 vials/kit
AOD-9604 2 mg/vial, 10 vials/kit
H 176-191 2 mg/vial, 10 vials/kit
CJC-1295 2 mg/vial, 10 vials/kit
CJC-1295 DAC 2 mg/vial, 10 vials/kit
***************************** *****************************
GHRP-2 5 mg/vial, 10 vials/kit
GHRP-6 5 mg/vial, 10 vials/kit
Selank 5 mg/vial, 10 vials/kit
***************************** *****************************
GHRP-2 10 mg/vial, 10 vials/kit
GHRP-6 10 mg/vial, 10 vials/kit
Epitalon 10 mg/vial, 10 vials/kit
PT-141 10 mg/vial, 10 vials/kit
Gonadorelin 10 mg/vial, 10 vials/kit
 

 
Packaging



Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment





Shipping Method



Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment






Company Information
Hubei Shinrezing Pharmaceutical Technology Co.,Ltd.(hereafter shorted as Shinrezing) is located in Wuhan Donghu High-Tech Economic Development Zone and established in 2008 with registered capital is RMB 10 million yuan (about USD 1.5 million ). Its manufacturing base is located in Dawu Industrial Park in Dawu County, Xiaogan City, Hubei Province which is built in 2010 with 25,000 square meters covered area.
 
Shinrezing is a rapid growing enterprise, which integrates the production, R&D, sales and trading of APIs, steroid raw materials, pharmaceutical intermediates, plant extracts, other kinds of organic intermediates etc. Shinrezing is not only a manufacturing company but also a trade company, it also has very good cooperation relationships with some manufacturers qualified with GMP, DMF to meet the different customers' needs from grams to tonnage quantity, which makes Shinrezing to be more flexible and easily to supply highly cost-effective products with high quality and better service to customers.
Shinrezing always stands in high starting, high stand and high quality, and masters strict management for production procedure and quality control. All the products must pass our quality test before being sending to customers. Shinrezing's products have been exported to more than 50 countries and regions all over the world, including United States, Europe, Japan, Korea, Russia, Hong kong, Taiwan and so on, and enjoy a good reputation from domestic and oversea customers
 
Shinrezing's mission is: "Innovative and Pragmatic, Mutual Benefits, Serve the World". Every staff member will keep this in mind all the time, and enforce it at every detail of operation and management of the company. We are always trying our best to offer the best services and the most competitive prices with high quality goods for our customers. All honors belong to the past, Shinrezing people will do their best to develop and produce more perfect product and contribute to the chemical pharmaceutical industries worldwide.

We are confident that Shinrezing will be your best solution.

Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment
Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment


 
FAQ
Order Guide
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , 
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
 
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 

Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we'd like to accept bank transfer, Western Union or Paypal or  Moneygram

Q6:How long does it take to the goods arrived ?
It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7  Do  you  have  any  reshipment  policy ?  
we have good after-sale service and re-shipment policy if the parcel  lose
Our long association with  our clients has brought great benefits
We always take the upmost care in the packaging of our products 
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible  will seize a small number of packages.
In this circumstance we promise reship free  to establish  long term relationship
 
Q8 :Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.
 
We have formed a technology and management team that cooperate closely with some  overseas Labs  all speak highly of our safe shipping and goods .
please donot hesitate to contact us.
 

Product Description
Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment

Acadesine/AICAR Powder CAS:2627-69-2

Alias:AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE
CAS:2627-69-2
EINECS:220-097-5
Molecular Formula:C9H14N4O5
Molecular Weight:258.23
Apperance: White or off-white powder.

Acadesine/AICAR Powder Description:

1. AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide.It can also be known as AICA ribonucleotide, ZMP, or Acadesine.It is an intermediate contained in the generation of inosine monophosphate.It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production.

2. AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).

3. AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion.

4. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion.Additionally, the peptide's presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.

Acadesine/AICAR Powder Biological Activity:

1. AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

2. Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCsin vitro.

Acadesine/AICAR Powder Functions:

1. AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.

2. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).

3. The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.

Analysis Report:
 

Item Specification Result
Appearance White powder Complies
Related substance (HPLC) Total impurity ≤0.5%
Max single impurity ≤0.1%		 0.2%
0.06%
Odor Characteristic Complies
Assay 99% 99.8%
Sieve analysis 100% pass 80 mesh Complies
Loss on Drying
Residue on Ignition		 ≤1.0%
≤1.0%		 0.12%
0.09%
Heavy Metal <10ppm Complies
As <0.1ppm 0.05ppm
Pb <0.1ppm 0.05ppm
Cd <0.1ppm 0.05ppm
Residual Solvents <100ppm Complies
Residual Pesticide Negative Complies
Microbiology    
Total Plate Count <1000cfu/g Complies
Yeast & Mold <100cfu/g Complies
E.Coli Negative Complies
Salmonella Negative Complies

 


Related Products 
Name CAS No. 
SR-9009 1165910-22-4
Rad-140 1182367-47-0
MK-677 159752-10-0
YK-11 431579-34-9
LGD-4033 1165910-22-4
GW-501516 317318-70-0
Andarine S4 401900-40-1
MK-2866 841205-47-8
Sunifiram 314728-85-3  
 

How to order quickly and safely? 

Step 1 (Inquiry) Please let me know the items you are favorable, quantities, and the destination country. 
Step 2 (Offer) We offer you price and the suitable shipping method for your reference. 
Step 3 (Negotiation) We will negotiate price, terms of payment, transport, delivery time, arrival time, destination of the goods and after-sales service. 
Step 4 (Order) After receiving your order, we will check it and get prepared for it. 
Step 5 (Payment) Please confirm the order and pay money 100% in advance, then send us the detailed contacting information, including contacting person/company, address, mobile number, ZIP code and your special requirements. 
Step 6 (Package & Delivery) Parcel will be arranged within 24 hours upon receipt of your payment. And photos will be offered to tell apart the products. 
Step 7 (Tracking number) If sent by EMS, the tracking number is availabe within 12 hours. The info will be trackable that day or next day. 
If sent by HKEMS or other express, the tracking number will be provided next day. And this does not mean the info is trackable that day. It will be released on internet 2 or 3 days later, because the parcel has to be shipped to Hongkong fist, and then wait for the flight. 
Step 8 (After-Sales Service) Within the terms of the contract, If there is any problem about the goods quality, quantity and other problems, we will assure you to make you satisfied with the results.  

Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment


  

Peptide List
 
Product Name Specification
ACE 031 1 mg/vial, 10 vials/kit
Follistatin 315 1 mg/vial, 10 vials/kit
Follistatin 344 1 mg/vial, 10 vials/kit
***************************** *****************************
Melanotan I 10 mg/vial, 10 vials/kit
Melanotan II 10 mg/vial, 10 vials/kit
MGF 2 mg/vial, 10 vials/kit
PEG - MGF 2 mg/vial, 10 vials/kit
DSIP 2 mg/vial, 10 vials/kit
TB500 2 mg/vial, 10 vials/kit
Oxytocin 2 mg/vial, 10 vials/kit
Hexarelin 2 mg/vial, 10 vials/kit
Triptorelin 2 mg/vial, 10 vials/kit
Ipamorelin 2 mg/vial, 10 vials/kit
Sermorelin 2 mg/vial, 10 vials/kit
Gonadorelin 2 mg/vial, 10 vials/kit
Tesamorelin 2 mg/vial, 10 vials/kit
BPC 157 2 mg/vial, 10 vials/kit
AOD-9604 2 mg/vial, 10 vials/kit
H 176-191 2 mg/vial, 10 vials/kit
CJC-1295 2 mg/vial, 10 vials/kit
CJC-1295 DAC 2 mg/vial, 10 vials/kit
***************************** *****************************
GHRP-2 5 mg/vial, 10 vials/kit
GHRP-6 5 mg/vial, 10 vials/kit
Selank 5 mg/vial, 10 vials/kit
***************************** *****************************
GHRP-2 10 mg/vial, 10 vials/kit
GHRP-6 10 mg/vial, 10 vials/kit
Epitalon 10 mg/vial, 10 vials/kit
PT-141 10 mg/vial, 10 vials/kit
Gonadorelin 10 mg/vial, 10 vials/kit
 

 
Packaging



Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment





Shipping Method



Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment






Company Information
Hubei Shinrezing Pharmaceutical Technology Co.,Ltd.(hereafter shorted as Shinrezing) is located in Wuhan Donghu High-Tech Economic Development Zone and established in 2008 with registered capital is RMB 10 million yuan (about USD 1.5 million ). Its manufacturing base is located in Dawu Industrial Park in Dawu County, Xiaogan City, Hubei Province which is built in 2010 with 25,000 square meters covered area.
 
Shinrezing is a rapid growing enterprise, which integrates the production, R&D, sales and trading of APIs, steroid raw materials, pharmaceutical intermediates, plant extracts, other kinds of organic intermediates etc. Shinrezing is not only a manufacturing company but also a trade company, it also has very good cooperation relationships with some manufacturers qualified with GMP, DMF to meet the different customers' needs from grams to tonnage quantity, which makes Shinrezing to be more flexible and easily to supply highly cost-effective products with high quality and better service to customers.
Shinrezing always stands in high starting, high stand and high quality, and masters strict management for production procedure and quality control. All the products must pass our quality test before being sending to customers. Shinrezing's products have been exported to more than 50 countries and regions all over the world, including United States, Europe, Japan, Korea, Russia, Hong kong, Taiwan and so on, and enjoy a good reputation from domestic and oversea customers
 
Shinrezing's mission is: "Innovative and Pragmatic, Mutual Benefits, Serve the World". Every staff member will keep this in mind all the time, and enforce it at every detail of operation and management of the company. We are always trying our best to offer the best services and the most competitive prices with high quality goods for our customers. All honors belong to the past, Shinrezing people will do their best to develop and produce more perfect product and contribute to the chemical pharmaceutical industries worldwide.

We are confident that Shinrezing will be your best solution.

Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment
Legit Sarms Powder Acadesine/Aicar 2627-69-2 for Cardiovascular Diseases Treatment


 
FAQ
Order Guide
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , 
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
 
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 

Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we'd like to accept bank transfer, Western Union or Paypal or  Moneygram

Q6:How long does it take to the goods arrived ?
It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7  Do  you  have  any  reshipment  policy ?  
we have good after-sale service and re-shipment policy if the parcel  lose
Our long association with  our clients has brought great benefits
We always take the upmost care in the packaging of our products 
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible  will seize a small number of packages.
In this circumstance we promise reship free  to establish  long term relationship
 
Q8 :Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.
 
We have for

Specifications
lpg gas cooker,Camping cooker parts adjusting fire arbitrarily,Suitable installed directly on the cylinder to make coffee, tea We are professional manufacturer ofLPG Gas Burner, LPG-cylinders,euro camping cylinders,valve,regulator,and different kinds of stoves and lamps.Also we offer some kinds of building shelf,some hardware and etc.Our products have send almost all over the world.With advanced process,stict testing,excellent quality and beautiful appearance,all our products are made of high quality materials.


LPG Gas Burner
1) the camping gas burner is suitable for any pan
2) Camping cooker parts adjusting fire arbitrarily
<1> portable type of camping gas burner,Convenient operation and easy to adjust the flame for your ideal cooking
<2> cold-rolled plate fingerprint-resistant SECC or stainless steel panel of the camping gas



We sell a variety of Gas Stove, such as natural gas stove, LPG gas stove, steel gas stove, outdoor gas stove,gas cooker stove, portable gas stove,and China gas stove and gas.



Gas Stove

Gas Stove, Cooking Stove, Camping Stove, Gas Cook Stove

ANSUN IMPORT AND EXPORT LIMITED. , http://www.ansungroup.com