Aquarium Shop Management Aquarium Fish
Ibrutinib is a small molecule drug that binds permanently to a protein, Bruton's tyrosine kinase (BTK) that is important in B cells; the drug is used to treat B cell cancers like mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenstrom's macroglobulinemia, a form of non-Hodgkin's lymphoma.
Ibrutinib Intermediates,Cas 330786-24-8,Cas 143900-44-1,High Purity Ibrutinib Intermediates Nanjing Sunshine Biotech Co., Ltd , http://www.sunshine-bio.com
New fish stocking
1. Do not rush to pour the fish into the tank. The plastic bag should be soaked in a pre-prepared fish tank for about 20 minutes to adjust the water temperature. Then open the bag and allow the fish to flow into the tank with the water.
2. Under normal circumstances, the same kind of fish is kept in the same tank. Sometimes the tank is not enough, and several different numbers of different fish can be kept together. However, they must take into account their requirements for water quality and temperature. The size and nature should be matched to avoid the phenomenon of large fish eating small fish and strong fish bullying weak fish.
3. The stocking density should be determined according to factors such as the fish body size and the type of fish, so as not to hinder the health of the fish.
4. For newly arrived tropical fish, do not feed bait within 3 days. Watch the fish's swimming status. After completely returning to normal, feed gradually from less to more.
Daily management
1. Choose bait. Tropical ornamental fish is a omnivorous fish mainly based on meat. In addition to artificial diets, it is also possible to cultivate animal foods such as fish and insects, bread and insects. Its palatability is good, and it is also more in line with the natural lifestyle of ornamental fish. Fish are very fond of eating, but also can reduce costs.
2. "Four set" feeding. That is, timing, positioning, qualitative, quantitative. The timing is to feed at a fixed time every day, from 9:00 to 10:00 in the morning and from 3:00 to 4:00 in the afternoon; the positioning is to feed the bait in a concentrated manner, prompting the fish to compete for food and reduce waste; The bait should be fresh, not mildewed, not rot, and the live bait must be rinsed and sterilized to prevent the putrefaction and various pathogens from being brought into the tank; the quantitative determination is based on the feeding conditions of the fish, generally 10 minutes to 15 minutes. The food is finished within minutes.
3. Water quality maintenance. To measure the temperature, pH and other indicators of water from time to time, if there is deviation from the normal range, it is necessary to make timely adjustments. For fish tanks with large breeding density or high requirements for culture water quality, oxygenators must be added to the fish tanks. Fish manure and food residues can contaminate the water quality so that the water quality does not meet the requirements of the fish. Therefore, the waste in the tank must be promptly discharged. Start the filter (do not affect the nighttime rest of the fish, preferably in the daytime), can drain away some of the dirt, and the filter twitches the water that flows through the filter layer and then sprays it into the fish tank. The water contacts the air and activates the water wave. There is also oxygen increase. In addition, the siphon principle is also used to suck the dirt from the bottom of the cylinder with a suction pipe. This process is best to stop the oxygenerator one hour after feeding in the morning and allow the water to settle for several hours.
2. Change water regularly. The number of water changes and the amount of water changed depend on the specific conditions of the water quality. Usually, it is changed from 3 days to 5 days. Each time the water is replaced by 1/5 to 1/3 of the original tank, the water for breeding is generally used in the sun for 2 days. ~3 days or tap water treated directly with bleach.
The water temperature should be similar to that of the original tank. If it is found that water quality deteriorates badly, you need to change the water or change the water.
Disease prevention and treatment
1. No disease first defense. Once the fish become ill, the treatment is troublesome, so it is very important to prevent the occurrence of fish diseases. Usually pay attention to the timing, appropriate amount of feed, regular water change, remove the waste in the aquarium, ensure the water quality is good, and the dissolved oxygen is sufficient. Ornamental fish live in an environment of excellent and stable water, and utensils should be disinfected before use. It is forbidden for the customer to slap the fish tank by hand. After the customer has specified the fish, the administrator can help to fish it so that the fish are not frightened.
2. Early treatment of illness. Regularly observe the fish's activity status and appearance, body color and flipper limbs. If any abnormalities are found, observe the fishes for isolation and treatment, and properly treat the seriously ill and dead fish to prevent infection. According to the correct diagnosis of the disease and timely prescribe the right medicine, medication should be strictly in accordance with the instructions, is strictly prohibited abuse of fishery drugs, blindly increase the amount of medication, increase the number of medication or prolong the use of drugs.
Management during the breeding season Many artificial tropical fish breeding techniques do not require high technology. In order to save costs, broodstock can be cultivated in the store and propagated.
1. The reproduction of fish. Breeding broodstock should be selected in the same age of the individual fish, bright color, shape standard, male and female fish with well-developed gonads, carefully feeding, nutritional supplements. For oviparous fish, such as angelfish, the females fertilize the eggs and in vitro fertilize the sperms of the males. According to their oviposition methods, the spawning water layer and the eggs are sticky, prepare the corresponding oviparous plates for spawning water. Layers, some also need to plant some aquatic plants. After the end of spawning, the broodstock should be removed in time to prevent the broodstock from eating the eggs. During the development of fertilized eggs, ensure that the dissolved oxygen in the water is sufficient, and remove the bad eggs in time. The sub-fish hatched within 2 days to 3 days, and they maintained their life activities by absorbing the nutrients in the yolk sac. For eggs born tropical fish, such as guppies, swordtail fish, etc., it directly outputs the fish that can swim, and after the fish is produced, the broodstock should be kept separately from the juvenile fish.
2. Rearing and management of juvenile fish. For 2 days to 3 days after hatching, and the child fish just out of the mother body is delicate, it must be ensured that there is sufficient open bait in the box, and the bait should be balanced. If the nutrition is not uniform, it will cause fish malformation or malnutrition. The open bait is best fed with small leeches or paramecium, rotifers, and can also be replaced with egg yolk and milk powder. Each feeding of bait should be appropriate. Excessive bait can easily degrade water quality. It should be sucked out with a straw after half an hour of feeding. Be careful not to activate the filter in the tank where the fish is raised to prevent the fish from being sucked away. In addition, the light on the aquarium can be moved to the side before feeding, and the phototaxis of the fish can be used to concentrate feeding. This method can also be used when changing the water, and when the fish swims to one side, the water is changed on the other side. Ten days after juvenile rearing, artificial fish can be used instead of grinding. After 10 days of feeding, the fish has reached a certain size and can be converted into crushed artificial bait. The individual juveniles have small individuals, and the disease is not easy to detect. It needs to be soaked with 3% saline or disinfectant every 10 days for 5 minutes to 10 minutes.
Ibrutinib is used to treat chronic lymphocytic leukemia, Waldenstrom's macroglobulinemia, and as a second-line treatment for mantle cell lymphoma, and marginal zone lymphoma.
We produce a series of complete intermediates for Ibrutinib, intermediate I (CAS No. 330786-24-8) and intermediate II (CAS No. 143900-44-1) etc.
All of our products are with stable production and strict quality control, making sure your experience with Sunshine Biotech is always enriching, satisfying and fulfilling.
