Bring new hope to improve sleep quality
Recently, Professor Feng Jianfeng, Dean of the Institute of Brain Intelligence Science and Technology of Fudan University, and the international cooperation team of researchers from the University of Warwick and Oxford University, for the first time, found the comorbid pathology of depression and sleep problems at the level of brain and nerve mechanism. mechanism. This achievement has brought new hope to improve the quality of sleep in the public, especially in patients with depression. Clinically, 70% of patients with depression have sleep problems, while those with sleep problems are also significantly more likely to suffer from depression or anxiety than those with normal sleep. This close relationship was discovered more than 100 years ago, but the brain mechanism behind the relationship between the two is not clear. In order to solve this mystery, the Sino-British cooperation team used the current popular technology, brain function image data, to analyze the brain image data and find the brain neural circuit that regulates the relationship between sleep quality and depressive symptoms. The Sino-British team integrated the two international brain imaging databases, the American Brain Connected Group Program (HCP) and the UK Biobank, and analyzed the image behavioral big data of nearly 10,000 subjects. Signal synchronization of the lateral marginal cortex (negative emotion-related brain function area), wedge leaf (self-related brain function area), and dorsal prefrontal cortex (short-term memory-related brain function area) in poorer people Sexually increased. At the same time, these neural circuits also showed a significant pattern of elevation in people with a higher tendency to score depression. Scientists have inferred that the synchrony of these signals is enhanced, regulating the relationship between depression and sleep. The connection between these brain regions is enhanced, which makes certain people's long-term negative emotions, leading to a decline in sleep quality. According to the latest statistics from the World Health Organization, there are more than 300 million people with depression in the world, which has increased by 18% in the past 10 years. Depression has been listed as one of the primary factors of disability in the World Health Organization. In this reality, the significance of this research to public health is particularly important. Finding the cranial nerve circuit associated with depression and sleep problems means that in the future it is possible to provide new target brain regions for the treatment of these two psychological problems at the clinical level. By specifically stimulating these brain regions, or simultaneously improving depressive symptoms and sleep problems, it will improve people's quality of life. Adequate sleep, a balanced diet and proper exercise are recognized health standards in the international community. Sleep problems are not only twin brothers of depression, but also associated with various stresses and diseases. The International Classification of Sleep Diseases contains more than 90 types of sleep disorders. The World Health Organization survey of nearly 26,000 people in 14 countries found that 27% of people have sleep problems, the insomnia rate in the United States is 32% to 50%, and Japan is 20%. China is over 30%. Sleep disorders have become a prominent problem that threatens the public health of countries around the world. Insufficient sleep not only seriously affects physical and mental health, but also brings huge economic costs. Workers with insomnia waste about 7.8 labor days per year on average due to sleep problems that result in reduced work efficiency. The social burden of various diseases caused by poor sleep quality is even more difficult to count. Sleep problems are a modern disease, but it takes time to solve this problem with modern medical technology. People's Daily (22 edition, August 16, 2018) Covid19 Pcr Kit,Sars-Cov-2 Test Kit,Sars-Cov-2 Pcr Test,Covid 19 Molecular Test Wuxi BioHermes Bio & Medical Technology Co., Ltd. , https://www.biohermesglobal.com