Mother's childhood may affect the child's memory

Release date: 2010-03-12

New research using mice has shown that the severity of childhood memory and learning disabilities may be affected by his or her mother's childhood experience. The researchers studied brain function in prepubertal mice with memory gene defects. Memory defects caused by inhibition of protein information by Ras-GRF1 and Ras-GRF2 were improved when these young mice were placed in a "advanced" environment exposed to stimuli, enhanced social interaction and active exercise for two weeks. After a few months, these mice were fertilized and their offspring had the same genetic defects. However, there are no signs of memory defects in future generations, even if they have never been exposed to the above-mentioned "advanced" environment like their mothers. “The most unique thing about this research is that we provided a “higher” environment in the pre-puberty of the first few months of the mouse's pregnancy, and the beneficial effects were passed on to the next generation.” The co-investigator of the study Dean Hutley said, "The descendants have improved their memory, even if they are not in a "higher" environment." To prove that future generations improve their memory, they are not in the "advanced" environment when their mother was young. Good "child care", some of the offspring are raised by "nursing mothers" who are not in a rich environment, but they still maintain improved memory. The example of “acquiring inheritance of traits” was first proposed by Jane Baptiste Lamarck in the early 19th century. However, this does not correspond to the classic Mendelian genetics, that is, we inherit the traits from our parents through specific DNA sequences, and they inherit their parents. Dr. Larry Feig, a professor of biochemistry at Tufts University School of Medicine, said, "The type of inheritance we are referring to now belongs to epigenetics, including environmental induction in DNA construction and the presence of DNA in the offspring. Variety."
This phenomenon indicates that research shows that adolescent activities affect the learning and memory of the next generation. However, it does not affect the next generations, because the role of the "advanced" environment in future generations will quickly diminish. The ability of a mouse to acquire at an early age can be inherited by its offspring. Meditech Medical Network

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