Function and classification of hyaluronic acid

Introduction to hyaluronic acid

Hyaluronic acid is a linear polysaccharide structure composed of a repeating structure of N-hexanoylglucosamine and D-glucuronic acid. Hyaluronan consisting of D-glucuronic acid and N-acetylglucosamine, also known as uronic acid, hyaluronic acid, the basic structure is composed of two disaccharide units D-glucuronic acid and N-acetyl A large polysaccharide composed of glucosamine. Unlike other mucopolysaccharides, it does not contain sulfur. Its hyaluronic molecule can carry more than 500 times of water, which is currently recognized as a good moisturizing ingredient of zui, and is widely used in skin care products and cosmetics.

With its unique molecular structure and physicochemical properties, hyaluronic acid shows various important physiological functions in the body, such as lubricating joints, regulating the permeability of blood vessel walls, regulating protein, water and electrolyte diffusion and operation, and promoting wound healing. It is especially important that hyaluronic acid has a special water retention effect and is a good natural moisturizing ingredient found in nature. It is called an ideal natural moisturizing factor.

Hyaluronic acid function

Hyaluronic acid itself has a negative charge and is present in most soft connective tissues in animals. Its aqueous solution is a viscoelastic fluid that fills the space of cells and collagen fibers and covers certain epidermal tissues. Hyaluronic acid (glass acid) HA is widely distributed in the connective tissue of the human body, and exists almost in a pure form in the vitreous body and the joint cavity. Hyaluronic acid (glass acid) HA present in the skin plays an important role in the metabolism of the human epidermis. The destruction or imbalance of hyaluronic acid (glass acid) HA in the human body can cause diseases. The reduction and destruction of the hyaluronic acid (glass acid) HA content in the skin can cause the skin to lose water, wrinkle and lose its elasticity, and cause the human epidermis to age. Therefore, hyaluronic acid (glass acid) HA is also known as anti-aging. factor.

Hyaluronic acid (glass acid) HA is one of the main matrix components of human skin epidermis and dermis. Its physiological function is to enable water to enter the intercellular space and combine with proteins to form a protein gel, which binds cells together and functions normally. The cell metabolism plays a role in maintaining cell moisture, protecting cells from pathogens, accelerating recovery of skin tissue, improving wound healing and regeneration, reducing scarring, and enhancing immunity. At the same time, hyaluronic acid is the main component of the extracellular matrix of proliferating cells and migrating cells, especially in embryonic tissues. Because of the inherent properties of hyaluronic acid, cells can be kept separate from each other, making cells easy to migrate and proliferate and prevent cell differentiation. During development, hyaluronic acid appears to prevent premature differentiation of cells before they multiply or migrate into place.

Hyaluronic acid classification

Cosmetic-grade hyaluronic acid

2. Pharmaceutical grade hyaluronic acid

3. Food grade hyaluronic acid

Hyaluronic acid precautions

1. Hyaluronic acid should be aseptically operated, limited to one use. Perfectha hyaluronic acid gel is forbidden after use.

2. When the joint inflammation is obvious, it is not suitable for injection. After the inflammation is eliminated, the Perfectha hyaluronic acid gel is injected.

3. When the joint effusion, discard the drainage as appropriate, Perfectha hyaluronic acid gel leaks outside the joint cavity will cause pain, so it must be injected into the joint cavity.

4. Sometimes it causes pain. After injection of Perfectha hyaluronic acid gel, it is quietly treated locally.

5. Hyaluronic acid in the case of disinfectant benzalkonium chloride, quaternary salt, etc., will produce precipitation, should be fully noted when used.

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